Anti-inflammatory and Antioxidative activities of Anthocephalus chinensis lamk (Rubiacea) extracts (methanol, chloroform and aqueous) were investigated. The methanol extract of the A. chinensis showed marked anti-inflammatory and free radical scavenging activities. The anti-inflammatory activity of the extracts at concentrations of 250 and 500 mg/kg was evaluated in carrageenan induced acute and formalin induced chronic inflammatory models in rats. The extracst showed remarkable antiinflammatory activity in both models, comparable to the standard reference drug diclofenac. The extracts of A. chinensisis fruit exhibited antioxidant properties at different concentrations when compared to standard (BHT) in the DPPH and NBT methods. The methanol extract exhibited the significant free radical scavenging activity. Results demonstrated that methanol extract of A. chinensis fruits may have the potential to be used as anti-inflammation and anti-oxidant.
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